Pharmacotherapy and Bumetanide in Autism Treatment

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Bumetanide in Children and Adolescents with Autism ‎Spectrum Disorder

Introduction: Autism Spectrum Disorder (ASD) is characterized by several impairments in communications and social interactions as well as restricted interests or stereotyped behaviors. Interventions applied for this disorder are based on multi-modal approaches, including pharmacotherapy. No cure or medication has been introduced so far; therefore, there were studies investigating several drugs ...

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Cognitive dysfunction and bumetanide treatment in a valproate-induced rat model of autism

Cognitive dysfunction is an important aspect of the clinical characteristics of autism; however, research has often focused on social cognition. Learning and memory disorders often occur in autistic children, which are particularly under examined. Using cognitive and behavioral measures in our study, these disorders were endorsed in a valproate-induced rat model of autism. We identified increas...

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ژورنال

عنوان ژورنال: Journal of Experimental and Basic Medical Sciences

سال: 2020

ISSN: 2717-9478

DOI: 10.5606/jebms.2020.75612